نتائج البحث

Steric hindrance and structural flexibility shape the functional properties of a guanine-rich oligonucleotide.

• Authors : Troisi R; Department of Chemical Sciences, University of Naples Federico II, Naples 80126, Italy.; Napolitano V

Subjects: Anticoagulants*/Anticoagulants*/Anticoagulants*/chemistry ; Aptamers, Nucleotide*/Aptamers, Nucleotide*/Aptamers, Nucleotide*/chemistry ; Thrombin*/Thrombin*/Thrombin*/chemistry

• Source: Nucleic acids research [Nucleic Acids Res] 2023 Sep 08; Vol. 51 (16), pp. 8880-8890.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Several structural motifs cooperate in determining the highly effective anti-thrombin activity of NU172 aptamer.

• Authors : Troisi R; Department of Chemical Sciences, University of Naples 'Federico II', Naples 80126, Italy.; Napolitano V

Subjects: Aptamers, Nucleotide/Aptamers, Nucleotide/Aptamers, Nucleotide/*chemistry ; Fibrinolytic Agents/Fibrinolytic Agents/Fibrinolytic Agents/*chemistry ; Thrombin/Thrombin/Thrombin/*chemistry

• Source: Nucleic acids research [Nucleic Acids Res] 2018 Dec 14; Vol. 46 (22), pp. 12177-12185.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Through-bond effects in the ternary complexes of thrombin sandwiched by two DNA aptamers.

• Authors : Pica A; Department of Chemical Sciences, University of Naples Federico II, Via Cintia, I-80126 Naples, Italy.; Institute of Biostructures and Bioimaging, CNR, Via Mezzocannone, 16, I-80134 Naples, Italy.

Subjects: Aptamers, Nucleotide/Aptamers, Nucleotide/Aptamers, Nucleotide/*chemistry ; Thrombin/Thrombin/Thrombin/*chemistry; Aptamers, Nucleotide/Aptamers, Nucleotide/Aptamers, Nucleotide/chemical synthesis

• Source: Nucleic acids research [Nucleic Acids Res] 2017 Jan 09; Vol. 45 (1), pp. 461-469. Date of Electronic Publication: 2016 Nov 28.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Different duplex/quadruplex junctions determine the properties of anti-thrombin aptamers with mixed folding.

• Authors : Russo Krauss I; Department of Chemical Sciences, University of Naples 'Federico II', Naples, Italy.; Institute of Biostructures and Bioimages, C.N.R, Naples, Italy.

• Source: Nucleic acids research [Nucleic Acids Res] 2016 May 05; Vol. 44 (8), pp. 3969.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Different duplex/quadruplex junctions determine the properties of anti-thrombin aptamers with mixed folding.

• Authors : Russo Krauss I; Department of Chemical Sciences, University of Naples 'Federico II', Naples, Italy Institute of Biostructures and Bioimages, C.N.R, Naples, Italy.; Spiridonova V

Subjects: Aptamers, Nucleotide/Aptamers, Nucleotide/Aptamers, Nucleotide/*chemistry ; Aptamers, Nucleotide/Aptamers, Nucleotide/Aptamers, Nucleotide/*metabolism ; Thrombin/Thrombin/Thrombin/*chemistry

• Source: Nucleic acids research [Nucleic Acids Res] 2016 Jan 29; Vol. 44 (2), pp. 983-91. Date of Electronic Publication: 2015 Dec 15.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Probing the activity of diguanylate cyclases and c-di-GMP phosphodiesterases in real-time by CD spectroscopy.

• Authors : Stelitano V; Istituto Pasteur-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, 00185 Rome, Italy.; Brandt A

Subjects: 3',5'-Cyclic-GMP Phosphodiesterases/3',5'-Cyclic-GMP Phosphodiesterases/3',5'-Cyclic-GMP Phosphodiesterases/*metabolism ; Circular Dichroism/Circular Dichroism/Circular Dichroism/*methods ; Cyclic GMP/Cyclic GMP/Cyclic GMP/*analogs & derivatives

• Source: Nucleic acids research [Nucleic Acids Res] 2013 Apr; Vol. 41 (7), pp. e79. Date of Electronic Publication: 2013 Jan 28.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity.

• Authors : Russo Krauss I; Dipartimento di Scienze Chimiche, Università di Napoli Federico II, Via Cintia, I-80126 Napoli, Italia.; Merlino A

Subjects: Aptamers, Nucleotide/Aptamers, Nucleotide/Aptamers, Nucleotide/*chemistry ; Thrombin/Thrombin/Thrombin/*chemistry; Cations/Cations/Cations/chemistry

• Source: Nucleic acids research [Nucleic Acids Res] 2012 Sep; Vol. 40 (16), pp. 8119-28. Date of Electronic Publication: 2012 Jun 04.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Thrombin-aptamer recognition: a revealed ambiguity.

• Authors : Russo Krauss I; Università di Napoli Federico II, Via Cintia, Napoli, Italia.; Merlino A

Subjects: Aptamers, Nucleotide/Aptamers, Nucleotide/Aptamers, Nucleotide/*chemistry ; Thrombin/Thrombin/Thrombin/*chemistry; Crystallography, X-Ray

• Source: Nucleic acids research [Nucleic Acids Res] 2011 Sep 01; Vol. 39 (17), pp. 7858-67. Date of Electronic Publication: 2011 Jun 28.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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